Dipeptidyl-Peptidase IV Inhibitors

Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.

Also Known As:

Dipeptidyl-Peptidase 4 Inhibitors; DPP 4 Inhibitor; DPP 4 Inhibitors; DPP IV Inhibitor; DPP IV Inhibitors; Dipeptidyl Peptidase 4 Inhibitors; Dipeptidyl Peptidase IV Inhibitor; Dipeptidyl Peptidase IV Inhibitors; Inhibitor, DPP-4; Inhibitor, DPP-IV; Inhibitor, DPP4; Inhibitor, Dipeptidyl-Peptidase 4; Inhibitor, Dipeptidyl-Peptidase IV; DPP-4 Inhibitor; DPP-4 Inhibitors; DPP-IV Inhibitor; DPP-IV Inhibitors; DPP4 Inhibitor; DPP4 Inhibitors; Dipeptidyl Peptidase 4 Inhibitor; Dipeptidyl-Peptidase 4 Inhibitor; Dipeptidyl-Peptidase IV Inhibitor; Gliptin; Gliptins

Chemical Actions and Uses
- Pharmacologic Actions: 164
  - Molecular Mechanisms of Pharmacological Action: 26
    - Enzyme Inhibitors: 1680
      - Protease Inhibitors: 6351
        Dipeptidyl-Peptidase IV Inhibitors: 2406
  - Physiological Effects of Drugs: 1
    - Hypoglycemic Agents: 15426
      - Dipeptidyl-Peptidase IV Inhibitors: 2406

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Disease

Drug/Important Bio-Agent (IBA)